Obesity& Immune Diseases
Do you know that
Obesity plays major role in triggering autoimmune diseases
Autoimmune diseases like Crohn’s Disease and multiple sclerosis, in which the immune system attacks its own body rather than bacteria and illnesses, affect 5-20% of the global community. Recent studies in autoimmunity reviews have found that obesity has a major role in causing autoimmune diseases.
ِِAccording to those researches, obesity leads to a breakdown of the body’s protective self-tolerance so creating appropriate environment for autoimmune diseases, and generates a pro-inflammatory environment likely to worsen the disease’s progression and impede its therapy.
As well as their own research, Prof. Shoenfeld and his team from Tel Hashomer hospital conducted a systematic review of 329 studies from around the world on the relationship between obesity, adipokines (compounds secreted by fat tissue and involved in numerous physiological functions, including the immune response), and immune-related conditions like rheumatoid arthritis, multiple sclerosis, type-1 diabetes, psoriasis, inflammatory bowel disease, psoriatic arthritis, and Hashimoto thyroiditis.
Prof.Shoenfeld said according to their study and clinical and experimental data that reviewed, the involvement of adipokines in the pathogenesis of these autoimmune diseases is clear, “We were able to detail the metabolic and immunological activities of the main adipokines featured in the development and prognosis of several immune-related conditions.”
Obesity in the world
2.1 billion people – nearly 30% of the world’s population – are either obese or overweight, according to a new, first-of-its kind analysis of trend data from 188 countries. The rise in global
Obesity and Diabetes
Obesity is also no longer a condition that just affects older people, although the likelihood does increase with age, and increasing numbers of young people have been diagnosed with obesity.
Obesity and Infertility
Obesity is defined as an abnormal accumulation of body fat, usually 20% or more over an individual’s ideal body weight.This is often described as a body mass index (BMI)
Obesity & Cancer
Obesity Linked to 13 Types of Cancer. 40% of Cancers Are Linked to Overweight and Obesity. Obesity increases the likelihood of developing many forms of cancer. The link between obesity
Obesity & Neurological Disorder
Influence of Obesity on Neurodegenerative Diseases. Gaining weight may desensitize the brain to the pleasure we get from sugary and fatty foods , prompting us to eat more cookies and cake
Obesity is rampant in the United States and is becoming increasing common worldwide. The increase in obesity prevalence is due to two major factors, plentiful supplies of inexpensive
OBESITY & LIVER DISEASES
Nonalcoholic fatty liver disease, or NAFLD, is an umbrella term for several stages of disease. Most people with NAFLD have what’s known as simple fatty liver, which means that more than 5% of the
Obesity in Egypt
Among the most populous countries in the world, the U.S. came on top with the highest rate of obesity among children and youth, namely 13 percent; while Egypt topped the list of obesity
Obesity & Hypertension
High blood pressure (hypertension) is a common health problem plaguing millions worldwide. Obesity is also an important public health problem with its high prevalence
Obesity & Osteoarthritis
The link between being overweight or obese and having osteoarthritis (OA) in weight-bearing joints is fairly easy to understand, though it may be underestimated. Being just 10 pounds overweight
OBESITY & SLEEP DISTRBANCE
Obesity-related sleep disorders improve markedly with weight loss. Sustainable weight loss should be a primary aim in the management of severely obese patients with significant sleep
OBESITY & GALL BLADDER DISEASES
Higher body mass index (BMI) appears to be a causal risk factor for gallstones, particularly for women, Danish researchers found. In a large population study, increasing BMI was associated
OBESITY & STROKE DISEASES
Obesity in Patients with Established Cerebrovascular Disease. The prevalence and consequences of obesity among stroke patients have not been thoroughly studied.